Structural Biology & Biomolecular Interactions Lab
The laboratory investigates G-quadruplex DNA structures, biomolecular spectroscopy, molecular recognition, protein–DNA interactions, and computational approaches for understanding biological systems at atomic resolution.
Publications
Spectroscopy Research
Faculty Laboratory
Structural Biology • Biomolecular NMR • DNA Interactions
Research Focus
Integrating structural biology, spectroscopy, computational simulations, and biomolecular interaction studies for understanding nucleic acid structures and therapeutic targeting.
Structural and thermodynamic investigations of G-quadruplex DNA relevant to cancer therapeutics and nucleic acid targeting.
Understanding molecular recognition and biomolecular interactions using structural biology and spectroscopic approaches.
Investigating anticancer compounds, natural products, and ligand interactions with nucleic acid structures.
Publications
Investigation of ligand-induced stabilization mechanisms in quadruplex DNA structures relevant to therapeutic targeting.
Combining spectroscopy and molecular simulations for studying conformational dynamics and nucleic acid interactions.
Contact
We welcome collaborations in structural biology, spectroscopy, nucleic acid interactions, computational biophysics, and molecular simulations.
Faculty
Department
Department of Biosciences and Bioengineering, IIT Roorkee
Research Areas
Structural Biology, G-Quadruplex DNA, Biomolecular NMR, Molecular Simulations